ASSOCIATION OF NON-ALCOHOLIC FATTY LIVER DISEASE WITH GLYCEMIC CONTROL OF DIABETES IN NON- OBESE TYPE 2 DIABETIC PATIENTS

Authors

  • Muhammad Umair Assistant Professor, Physiology Department, Gomal Medical College, D.I. Khan.
  • Muhammad Omar Malik Assistant Professor, Physiology Department, Institute of Basic Medical Sciences, Khyber Medical University, Peshawar
  • Azhar Ijaz Associate Professor, Physiology Department, Loralai Medical College, Loralai.
  • Ameena Palwasha Senior Lecturer, Physiology Department, Jinnah Medical College, Peshawar.
  • Kinza Sammar Associate Professor, Physiology Department, Abbottabad International Medical Institute, Abbottabad.
  • Hafsa Bashir Dental Surgeon, Department of Dentistry, Civil Hospital Thana, Malakand.

DOI:

https://doi.org/10.70905/bmcj.06.01.0482

Keywords:

Non-alcoholic fatty liver disease (NAFLD),, Type 2 diabetes mellitus (T2DM), hyperglycemia, fasting blood sugar (FBS) levels, Random blood sugar (RBS) levels, Glycosylated Hemoglobin (HbA1c)

Abstract

Abstract

Background: Non-alcoholic fatty liver disease (NAFLD) involves diffuse fat accumulation in hepatocyte and is frequently associated with metabolic conditions like obesity, Type 2 Diabetes Mellitus (T2DM), and hyperlipidemia. Despite its asymptomatic nature, NAFLD is commonly detected via ultrasonography, even in non-obese diabetic individuals. This study explores the relationship between NAFLD and diabetic glycemic control.

Objective: This research work assesses the association between NAFLD and glycemic control in non-obese Type 2 Diabetes Mellitus (T2DM) patients.

Material and Methods: A cross-sectional study was conducted on 100 diagnosed T2DM patients with BMI in range of 18.5±29.9. The sample included 55 males and 45 females, with a mean age of 46.78 ± 8.39 years (range: 30–60 years). NAFLD was diagnosed via ultrasound, and glycemic control was evaluated using HbA1c, fasting blood sugar (FBS), and random blood sugar (RBS) levels.

Results: No significant association was found between NAFLD and HbA1c (p=0.826), FBS (p=0.778), or RBS (p=0.817), even without adjusting for confounders such as age, sex, BMI, medication, insulin use, and lipid levels.

Conclusion: NAFLD does not influence glycemic control in T2DM patients, as indicated by HbA1c, FBS, and RBS levels.

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Published

2025-06-30

How to Cite

Umair, M. ., Omar Malik, M. ., Ijaz, A. ., Palwasha, A. ., Sammar, K. ., & Bashir, H. . (2025). ASSOCIATION OF NON-ALCOHOLIC FATTY LIVER DISEASE WITH GLYCEMIC CONTROL OF DIABETES IN NON- OBESE TYPE 2 DIABETIC PATIENTS. BMC Journal of Medical Sciences, 6(1), 24–28. https://doi.org/10.70905/bmcj.06.01.0482

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Original Articles