ASSOCIATION OF NON-ALCOHOLIC FATTY LIVER DISEASE WITH GLYCEMIC CONTROL OF DIABETES IN NON- OBESE TYPE 2 DIABETIC PATIENTS
DOI:
https://doi.org/10.70905/bmcj.06.01.0482Keywords:
Non-alcoholic fatty liver disease (NAFLD),, Type 2 diabetes mellitus (T2DM), hyperglycemia, fasting blood sugar (FBS) levels, Random blood sugar (RBS) levels, Glycosylated Hemoglobin (HbA1c)Abstract
Abstract
Background: Non-alcoholic fatty liver disease (NAFLD) involves diffuse fat accumulation in hepatocyte and is frequently associated with metabolic conditions like obesity, Type 2 Diabetes Mellitus (T2DM), and hyperlipidemia. Despite its asymptomatic nature, NAFLD is commonly detected via ultrasonography, even in non-obese diabetic individuals. This study explores the relationship between NAFLD and diabetic glycemic control.
Objective: This research work assesses the association between NAFLD and glycemic control in non-obese Type 2 Diabetes Mellitus (T2DM) patients.
Material and Methods: A cross-sectional study was conducted on 100 diagnosed T2DM patients with BMI in range of 18.5±29.9. The sample included 55 males and 45 females, with a mean age of 46.78 ± 8.39 years (range: 30–60 years). NAFLD was diagnosed via ultrasound, and glycemic control was evaluated using HbA1c, fasting blood sugar (FBS), and random blood sugar (RBS) levels.
Results: No significant association was found between NAFLD and HbA1c (p=0.826), FBS (p=0.778), or RBS (p=0.817), even without adjusting for confounders such as age, sex, BMI, medication, insulin use, and lipid levels.
Conclusion: NAFLD does not influence glycemic control in T2DM patients, as indicated by HbA1c, FBS, and RBS levels.



