RELATIONSHIP BETWEEN LEFT ATRIAL THROMBUS AND ATRIAL FIBRILLATION IN RHEUMATIC MITRAL VALVE HEART DISEASE PATIENTS

Authors

  • Mariya Qazi Senior Registrar of Cardiology Bilawal Medical College, Liaquat University of Medical and Health Sciences Jamshoro
  • Muhammad Ali Bohyo Director Institutes of Biomedical Engineering and Technology, LUMHS, Jamshoro

DOI:

https://doi.org/10.70905/bmcj.06.01.0490

Keywords:

Atria fibrillation (AF),, Left Atrial Thrombus(LAT), Mitral stenosis(MS), Rheumatic heart disease (RHD)

Abstract

Abstract

Background: The development of left atrial (LA) thrombus and the risk of embolization are common complications in individuals with mitral stenosis (MS). In cases of rheumatic heart disease (RHD), multiple factors influence thrombus formation in the left atrium, with atrial fibrillation and the severity of mitral stenosis being the most significant contributors.

Objective: This research aimed to investigate the association between left atrial thrombus and atrial fibrillation in patients with rheumatic mitral valve heart disease.

Material and Methods: It is a descriptive observational prospective study. This research took place at LUMHS Jamshoro/Hyderabad. Patients admitted with 120 individuals with comprehensive clinical histories and examinations suggestive of rheumatic mitral valve disease were included in the study through a non-probability purposive sampling method from January 2022 to December 2022. Electrocardiography was done for atrial fibrillation and a non-invasive Tran thoracic and semi-invasive Tran esophageal echocardiography (TEE) was conducted utilizing advanced imaging technology ultra mark 6 ultrasound Toshiba in recently identified atrial fibrillation individuals, to evaluate left atriumorLA appendage thrombus.

Results: The average age of patients in this research was 37.83 ± 16.39 years. Females constituted the larger proportion, representing 80 (66.7%) participants, while males accounted for 40 (33.3%). Shortness of breath and palpitations were the most commonly reported symptoms, occurring in 92 (76.7%) and 54 (45.0%) cases, respectively In this research, as correlation was observed between atrial fibrillation and left atrial thrombus.(p-value  0.01).

Conclusion: This study found a strong association between atrial fibrillation and the occurrence of a thrombus in the LA.   All patients who underwent Tran thoracic echo and are found to have larger left atrial diameters must undergo TEE to exclude LAT as TTE very low sensitivity for Left atrial thrombus.

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Published

2025-06-30

How to Cite

Qazi, M. ., & Ali Bohyo, M. . (2025). RELATIONSHIP BETWEEN LEFT ATRIAL THROMBUS AND ATRIAL FIBRILLATION IN RHEUMATIC MITRAL VALVE HEART DISEASE PATIENTS . BMC Journal of Medical Sciences, 6(1), 64–67. https://doi.org/10.70905/bmcj.06.01.0490

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Section

Original Articles